Define the unit before entering data

If one person can have multiple episodes, decide how those will be represented. Otherwise, repeated reports may be mistaken for separate cases or genuine episodes may be merged.

Use a stable investigation identifier and keep identifying information appropriately protected.

A focused starting structure

Field groupExample content
IdentificationUnique case or episode code
TimingOnset, specimen, and report dates
ClassificationCurrent case status and version
Clinical informationRelevant symptoms and outcomes
ExposureDefined exposures in the relevant period

The actual fields depend on the investigation. Collecting every imaginable variable can slow work and increase privacy risk.

Unknown is not no

Use explicit codes for unknown, not asked, not applicable, and absent when those distinctions matter. A blank cell should not silently become a negative exposure.

Preserve updates

Case status and dates may change as information improves. Record the source and update history rather than overwriting important uncertainty without a trace.

A line list is a working investigation tool, not a static spreadsheet created once. Clear definitions, validation checks, controlled access, and regular review make later curves and comparisons more trustworthy because the underlying records remain interpretable.